What New Research Says about Muscle Growth

Training Close to Failure for Growth and Strength: What New Research Says about Muscle Growth

Does training close to muscular failure promote greater muscle growth?

And is there a point where training to failure begins to impede strength gains?

Want to know what new research says about muscle growth?

A 2024 series of exploratory meta-regressions led by researchers at Florida Atlantic University and collaborating institutions examined these questions.

The researchers analyzed data from 55 studies and used exploratory meta-regression models to examine the relationship between estimated repetitions in reserve (RIR), muscle hypertrophy, and strength.

The results were informative.

The analysis found that, for muscle hypertrophy, sets terminated closer to failure were associated with greater increases in muscle size. However, the researchers cautioned that the exact dose-response relationship remains uncertain because RIR had to be estimated from the available studies.

By contrast, when it came to strength, the difference between a wide range of RIR values was minimal throughout most of the range.

This does not mean that one should always train to failure.

It does suggest that, when it comes to hypertrophy, one should consider the value of RIR more carefully than when it comes to strength.

Quick Answer: Should You Train Close to Failure?

If building muscle is your primary objective, current evidence indicates that training close to the point of failure on a regular basis is likely to be advantageous.

If maximal strength is your main goal, going to near failure on every set is not necessarily required, as heavier loads, improved technique, appropriate specificity, and fatigue management contribute significantly towards additional strength gains.

The 2024 Florida Atlantic University meta-regression showed that the proximity to failure was associated with greater hypertrophy, while the relationship to strength was trivial. The authors noted that the true value of proximity to failure was challenging to establish due to the need to estimate the number of repetitions in reserve from the available studies.

A short summary would be:

Training close to failure can be beneficial for hypertrophy, but strength gains can occur across a relatively wide range of RIR.

Table of Contents

  • Muscle Hypertrophy vs. Strength: What’s the Difference?
  • What Does Training to Failure Actually Mean?
  • What the 2024 Research Found
  • Why Proximity to Failure May Matter for Muscle Growth
  • Does Training to Absolute Failure Build More Muscle?
  • Why Strength Training May Not Require Near-Failure Sets
  • Why Strength Training May Not Require Near-Failure Sets?
  • How Close to Failure Should You Train for Muscle Growth?
  • How Close to Failure Should You Train for Strength?
  • Does Training Load Change the Equation?
  • What About Repetition Tempo?
  • Does Training at Longer Muscle Lengths Build More Muscle?
  • How Exercise Selection Affects Training to Failure
  • How to Combine Muscle Growth and Strength Training
  • A Practical Training Framework
  • Common Mistakes When Training Close to Failure
  • Frequently Asked Questions
  • Key Takeaways
  • Conclusion

Muscle Hypertrophy vs. Strength: What’s the Difference?

Before talking about failure, I want to distinguish two goals that are often conflated.

Muscle Hypertrophy

Muscle hypertrophy is increased muscle size. If your goal is to have big arms, shoulders, chest, back, legs, etc., you are training for hypertrophy.

If you’re interested in the relationship between muscle hypertrophy and body composition, we’ve also examined whether gaining muscle is really the key to getting lean.

There are several factors that affect hypertrophy, including:

  • training volume
  • resistance
  • proximity to failure
  • exercise selection
  • range of motion
  • training frequency
  • nutrition
  • recovery
  • No single factor exclusively determines hypertrophy.

Strength

Strength is the ability to generate force.

If your goal is to increase your squat, bench, deadlift, overhead press, or any other specific lift, your training is similar to hypertrophy training but with some important differences.

As with hypertrophy, there are several factors that affect strength, including:

  • muscle size
  • nervous-system adaptations
  • technique
  • coordination
  • lifting experience
  • specificity of training
  • load used during training

This is why you can get stronger without getting much bigger.

Strength training also offers benefits beyond simply increasing muscle size or lifting heavier weights, as explained in our guide to the benefits of strength training.

What Does Training to Failure Actually Mean?

Muscular failure is when you can’t complete another repetition with proper form and range of motion on a set.

Say, for instance, you’re doing dumbbell curls.

If you get to your eighth repetition and know that you can’t complete another one, you’ve hit momentary muscular failure.

But you don’t need to reach that point to have a challenging set.

You may have the sense to stop at the point where you feel that you could do:

  • 5 more repetitions
  • 3 more repetitions
  • 2 more repetitions
  • 1 more repetition

These are referred to as repetitions in reserve, or RIR.

Know Your RIR

RIR: What it means?

  • 5 RIR You feel you could complete approximately five more repetitions
  • 4 RIR You feel you could complete approximately four more repetitions
  • 3 RIR You feel you could complete approximately three more repetitions
  • 2 RIR You feel you could complete approximately two more repetitions
  • 1 RIR You feel you could complete approximately one more repetition
  • 0 RIR You’ve reached muscular failure

RIR is an approximation, not a scientific finding.

And that’s where we should probably take it. The the 2024 meta-regression used estimated RIR scores based on the descriptive summaries of the studies.

The researchers therefore specifically cautioned that the precise relationship between RIR and hypertrophy or strength gains remains uncertain.

What the 2024 Research Found

The study that generated the headline “For Bigger Muscles, Push Close to Failure, For Strength, Maybe Not” was published in Sports Medicine in 2024.

The researchers pooled data from 55 studies and used a set of meta-regression models to explore the possibility that the distance from failure was associated with different outcomes in terms of muscle hypertrophy and strength gains.

The findings were interesting, but one must keep in mind that it is still an exploratory work.

For Muscle Hypertrophy

the best-fitting models showed that muscle growth was positively associated with closeness to failure.

In other words, the closer the sets ended to failure, the greater the hypertrophy.

For Strength

However, the findings were mixed.

The confidence intervals of the estimated relationships between RIR and strength encompassed a null association, suggesting that strength gains were similar across a relatively wide range of RIR.

The researchers concluded that proximity to failure appears to be associated more closely with hypertrophy than with strength.

But there is an Important Caveat

The study does not prove that everyone should train to absolute failure.

It also does not show that stopping precisely at 1 RIR, for example, is universal.

The researchers described the analysis as exploratory and highlighted limitations related to the estimation of RIR.

Broader Takeaway: A useful takeaway is that getting reasonably close to failure appears more important for hypertrophy than for strength, but the exact optimal point is not established.

Why Proximity to Failure May Matter for Muscle Growth

As the set goes on, it becomes harder to make more reps.

The closer the point of failure gets, the more effort needed to keep producing force.

This can place the working muscle under substantial mechanical tension and fatigue.

Which does not mean that every single set must end with a failed rep.

This does not mean that every set needs to end in failure. However, stopping a set very early, when many technically sound repetitions remain possible, may provide less of a hypertrophic stimulus than training sufficiently close to failure.

Earlier systematic-review evidence provides a useful counterpoint.

A systematic review and meta-analysis found only a trivial overall benefit for some definitions of training to failure compared with non-failure training, while finding no clear superiority for momentary muscular failure specifically. The authors concluded that the relationship between proximity to failure and hypertrophy may be nonlinear.

The newer 2024 meta-regression adds evidence that closer proximity to failure is associated with greater hypertrophy.

However, it should be interpreted alongside earlier evidence suggesting that the relationship may not be linear and that momentary muscular failure itself has not been shown to be clearly superior to non-failure training.

Does Training to Absolute Failure Build More Muscle?

Not necessarily.

This is one of the most crucial differences.

Training close to failure is not the same thing as training to failure.

For many hypertrophy-focused sets, stopping with one or two technically sound repetitions still available can provide a useful balance between training stimulus and fatigue.

When you take every set to failure, you run the risk of creating excessive fatigue that can compromise:

  • the quality of subsequent sets,
  • workout volume,
  • technique,
  • recovery,
  • your performance in the current workout,
  • your performance in the following training session.

A systematic review and meta-analysis found no clear overall advantage of training to failure for maximal strength and no evidence that momentary muscular failure is required to produce muscle hypertrophy.

Therefore, the idea that “every set has to be taken to failure” is not an accurate maxim for maximizing hypertrophy.

The more accurate maxim would be to train intensely enough to stimulate the targeted muscles while avoiding undue fatigue so that you can achieve high-quality subsequent sets.

Training intensity is only one part of the equation. Nutrition and energy balance also matter when your goal is building muscle for fat loss while maintaining performance.

Why Strength Training May Not Require Near-Failure Sets

The most interesting finding of the 2024 study, perhaps, is what it didn’t find.

Estimated proximity to failure showed a much lower association with increases in strength than with hypertrophy.

It makes perfect sense. Strength is not only a function of hypertrophy.

It also reflects your ability to:

  • perform the movement skillfully and have good movement quality
  • generate greater levels of force
  • learn the movement pattern
  • maintain technique under greater loads
  • practice the lifts

For instance, when learning to improve your 1RM squat, you must practice squatting with relatively heavy loads, but you need not always go to the point where you cannot do another repetition, and doing so may, in fact, compromise your ability to perform the lift correctly as fatigue builds up.

If you’re new to resistance training, our step-by-step guide to beginner strength training covers the fundamentals before you start worrying about advanced concepts such as training to failure.

Why Strength Training May Not Require Near-Failure Sets

Reps in reserve is a pragmatic way of expressing – ‘I can still do 2 more reps.’

Instead of saying:

“I trained at 85% intensity”

You should say:

“I did that set with approximately 2 RIR”

This means, you could have done 2 more reps with good form.

Why RIR can be Helpful?

Using RIR helps you modulate efforts without always forcing sets to failure.

For example:

Hypertrophy-Focused Training

Where you may often be training with intensities of roughly 0-3 RIR depending on the exercise, working load, experience level and periodization strategy

Strength-Focused Training

This may involve leaving more reps in the tank (higher RIR) when doing heavy compound movements while still using sufficiently challenging working loads.

These are some examples of how the findings can be applied, they are not hard and fast rules as implied by the 2024 meta-analysis.

How Close to Failure Should You Train for Muscle Growth?

If hypertrophy is your primary objective, the existing evidence base does support doing many working sets reasonably close to failure.

As a practical starting point, many lifters may choose to perform most hypertrophy-oriented sets with roughly 1–3 RIR. This should be viewed as a practical programming guideline rather than a precise range established by the 2024 meta-regression.

For example:

Isolation Exercises

Exercises such as:

  • biceps curls
  • triceps extensions
  • lateral raises
  • leg extensions
  • leg curls

can often be taken fairly close to failure, as the exercises are easier to control and generally induce less whole-body fatigue.

Compound Exercises

Exercises such as:

  • squats
  • deadlifts
  • barbell rows
  • bench presses
  • overhead presses

can produce considerably more systemic fatigue, so you may want to stop a little further from absolute failure, especially once your technique begins to suffer.

The goal is not to make every set maximally exhausting, but to create sufficient stimulus to promote adaptation while preserving the quality of your training.

How Close to Failure Should You Train for Strength?

For strength-oriented training, the data do not suggest that you should always train close to failure.

The 2024 meta-regression found that strength gains were comparable across a broad range of estimated RIR.

This implies greater flexibility in programming.

A strength-oriented program may involve:

  • a heavier load
  • fewer repetitions
  • longer rest between sets
  • more repetition in reserve
  • greater technical focus
  • more specific sets

For example, if your goal is to increase your squat 1RM, it may be more important to practice squats with a heavier load and greater focus on proper technique than to regularly take each set to the point of failure.

Similarly, the evidence suggests that higher loads confer greater increases in maximal strength, even if a wide range of loads can lead to substantial hypertrophy.

Does Training Load Change the Equation?

Yes.

One of the most interesting results of resistance-training research is that hypertrophy can be achieved with a wide variety of loads, as long as the training is sufficiently challenging.

Strength gains can also occur across a range of loads, but heavier loads tend to provide an advantage for developing maximal strength, particularly when strength is tested with heavy loads.

This is one reason why a hypertrophy workout and a strength workout might look different.

For Hypertrophy

You have a lot of flexibility in the load.

For Strength

Training with a heavier load becomes more important because the adaptation is specific to produce force against a heavy load.

This doesn’t mean that lighter loads aren’t helpful for strength.

But it does mean that training heavier has a specific benefit when maximal strength is your intended outcome.

What About Repetition Tempo?

The original version of this article suggested a specific 4-1-1-0 tempo for hypertrophy.

I would no longer make that recommendation.

The evidence doesn’t support asserting one specific tempo as the secret to hypertrophy.

Earlier research had found similar levels of hypertrophy across a fairly broad spread of repetition durations, and a 2025 systematic review and meta-analysis found overall minimal difference between faster and slower resistance training tempos.

So how should you perform your repetitions?

A better recommendation is controlling the weight, using a consistent range of motion, and not decelerating repetitions to such an extent that the load is too light to train effectively.

The eccentric phase should be controlled, not simply allowed to drop to the bottom of the range of motion due to gravity alone.

However you do not need to count:

4 seconds down + 1 second pause + 1 second up

on every repetition in order to hypertrophy.

Technique, effort, load, training volume, range of motion, and progressive overload are generally more useful programming considerations than trying to identify one specific tempo that maximizes hypertrophy.

Does Training at Longer Muscle Lengths Build More Muscle?

Another interesting area of current research is training muscles at longer muscle lengths.

The concept is simple.

Some exercises are done in a way in which a muscle is heavily loaded when it is lengthened.

Examples can be:

  • Romanian deadlifts for the hamstrings
  • deep squats for the quads and glutes
  • overhead triceps extensions
  • incline curls for the biceps

Some recent research suggests that training muscles at longer muscle lengths may promote greater hypertrophic adaptations in certain circumstances. However, the evidence is still developing, and findings are not uniformly consistent across exercises and muscles.

A 2025 systematic review examining longer-muscle-length resistance training found potentially favorable effects on measures related to longitudinal muscle growth, but the authors also highlighted limitations in the available evidence.

Therefore, the practical takeaway is not:

“Every exercise must stretch the muscle as much as possible.”

Instead,

“Choose exercises that train the target muscle through an appropriate range of motion and, where appropriate, challenge it at longer muscle lengths without sacrificing technique or comfort.”

FAQs on Muscle Growth and Failure

How Exercise Selection Affects Training to Failure

The closer you train to failure, the more important exercise selection becomes.

Consider these two exercises.

A Bicep Curl vs a Heavy Barbell Squat?

If you reach muscular failure on an isolated biceps curl, the consequences are localized: your biceps are fatigued.

If you reach failure on a heavy squat, fatigue can substantially affect technique, balance, bracing, and repetition quality.

Consider reserving the closest-to-failure work for exercises you can perform safely and consistently with good technique.

A wise consideration given a person’s stability, technical capacity, history of injuries, level of experience, and general fatigue: save the close-to-failure work for movements you’re most capable in.

How to Combine Muscle Growth and Strength Training?

You don’t have to choose between getting big and getting strong. Many resistance training programs can be tailored to do both.

The key is to understand that the emphasis may need to be different.

If Hypertrophy is a Priority:

  • training should be focused on
  • achieving sufficient training volume per week
  • using multiple hard sets,
  • a variety of effective loads,
  • and sets performed relatively close to failure,
  • as well as progressive overload,
  • along with adequate protein and calories,
  • and sufficient recovery.

If Strength is a Priority:

  • focus should be on
  • heavy loads,
  • lower repetition ranges,
  • technical proficiency,
  • specificity of lifts,
  • adequate rest,
  • fatigue management,
  • and progressive loading.

And if you want both, you can do both. Nutrition matters too, particularly when you’re trying to support recovery and adaptation; our guide explains how to choose protein for muscle recovery.

A workout could, for example, begin with a heavy compound movement performed with several repetitions in reserve, followed by moderate-repetition accessory work performed closer to failure. This way you can practice strength specific movements without having to tax every set to the limit.

A Practical Training Framework

Here’s a simple framework based on the current evidence.

Goal Typical approach Proximity to failure Main priority
Muscle hypertrophy Moderate-to-high volume Generally close to failure Volume, effort, progressive overload
Maximal strength Heavier loads, lower reps Failure usually unnecessary Load, specificity, technique
Both Combine heavy and moderate-load work Varies by exercise Balance stimulus and fatigue

These are guidelines.

Not hard and fast rules.

You don’t have to do every exercise just this way.

Your training experience, choice of exercises, ability to recover, and your goals should all factor in to your decisions.

Training Frequency and Muscle Growth

Another consideration is how often a muscle is trained.

Training frequency is another part of the equation, but it should not be viewed independently of total training volume.

Do not assume that taking every set to absolute failure is the best way to increase training stimulus. The goal is to accumulate enough productive work while maintaining recovery and performance across the week.

Practical application:

Do not try to push each set to absolute failure as that will not necessarily lead to superior results.

Adequate training volume (and hence workload) combined with adequate recovery are essential for muscle growth.

Training to failure on every set may not be as effective as performing a lower total training volume without pushing to failure.

Common Mistakes When Training Close to Failure

Mistake 1: Taking every set to absolute failure

While training to failure can be occasionally useful, it is by no means obligatory for each set.

In fact, repeated failure training can compromise your performance capacity.

Mistake 2: Confusing discomfort with failure

You might be able to feel a challenging set, but that doesn’t mean you have reached a point of muscular failure.

A burning sensation in the muscles, discomfort, and difficulty in breathing aren’t necessarily synonymous with the inability to perform another technically acceptable repetition.

Mistake 3: Sacrificing technique

If your technique has changed significantly in order to complete another repetition, then the set has likely passed the point of being productive for the targeted muscles.

Mistake 4: Using the same RIR for every exercise

A heavy squat and a machine-based biceps curl do not impose the same technical, stability, muscular, or whole-body demands, so the appropriate proximity to failure may differ between them.

Mistake 5: Believing that slower repetitions automatically produce more muscle

Current evidence suggests that repetition tempo has a relatively small overall effect on hypertrophy, although specific training conditions may produce different responses.

Mistake 6: Ignoring progressive overload

Coming close to failure isn’t the sole determinant to continue making progress in the gym.

Progressive overload means gradually increasing the training challenge over time. This can involve adding weight or repetitions, increasing training volume when appropriate, improving execution or range of motion, or otherwise increasing the stimulus while maintaining good technique.

A quick overview:

  • more sets
  • more repetitions
  • more weight
  • more effective technique
  • and better execution.

Mistake 7: Ignoring recovery

Muscle growth doesn’t happen simply because of the mechanical stimulus of a workout; it also depends on adequate recovery, nutrition, sleep, and the ability to perform future training sessions effectively.

Frequently Asked Questions:

Is training to failure necessary for muscle growth?

No.

The latest evidence doesn’t show that each set has to be taken to absolute failure to maximize muscle growth.

The 2024 meta-regression found that the closer you train each set to failure (i.e., the lower the RIR), the better the results for muscle growth, but the optimal range for most people has yet to be established.

How many reps should I leave in reserve for muscle growth?

For most people, a good starting point would be to train 1 to 3 RIR on most sets.

It’s an imperfect system, but it’s a decent one.

Some sets may be closer to failure than others, based on the exercise and training phase.

How many reps should I leave in reserve for strength?

You probably do not want to train as close to failure as you do when pursuing muscle size.

The same 2024 analysis found that there was essentially no relationship between RIR and increases in strength.

Strength training may leave more reps in reserve.

Is RIR better than 2 RIR for muscle growth?

Not necessarily.

The 2024 meta-regression found that hypertrophy increased as estimated RIR decreased, suggesting that sets performed closer to failure may provide greater hypertrophic stimulus. However, the researchers cautioned that the exact dose-response relationship remains uncertain because RIR was estimated from the available studies. The analysis therefore does not establish that 0 RIR is definitively superior to 2 RIR for everyone.

Should beginners train to failure?

Beginners generally do not need to train to failure on every set.

If you are new to training, you want to prioritize learning proper form, gaining experience with the movements, and building a training base.

Failure for hypertrophy is not essential for novices.

Should compound exercises be taken to failure?

Not necessarily.

Compound lifts are already technically and mentally demanding.

Leaving a few repetitions in reserve on heavy compound exercises can help you recover better and get more work done in the long run.

Are isolation exercises better for training to failure?

Isolation exercises may be best for training to failure — but not because they are intrinsically better for muscle growth.

They are simply less technically and mentally demanding, so they are safer to train close to failure on.

Does training to failure increase muscle damage?

Resistance training can cause some degree of muscle damage, particularly when the training stimulus is unfamiliar or demanding, but muscle damage itself is not considered a prerequisite for hypertrophy.

Does training close to failure increase recovery time?

Training to failure can increase acute fatigue compared with stopping further from failure.

The question is not whether training to failure causes more fatigue, but rather whether that extra fatigue will hurt performance in subsequent sets and workouts.

Is heavy weight better for building muscle?

Not necessarily.

Systematic reviews and meta-analyses have found that muscle hypertrophy can be achieved across a relatively wide range of resistance loads when training is sufficiently challenging.

However, there is a growing amount of evidence that heavy resistance is needed to maximize strength gains.

Is slow training better for muscle growth?

Current evidence suggests that hypertrophy can occur across a fairly broad range of repetition tempos, with the overall effect of tempo appearing relatively small. The 2025 systematic review and meta-analysis found minimal overall differences between faster and slower tempos, although individual training conditions may differ.

Should every workout be close to failure?

No, it should not.

A well-rounded program can use different rep ranges and effort levels depending on your goals, exercise selection, and recovery capacity.

Key Takeaways

The most recent research offers a valuable distinction between training for hypertrophy and training for strength.

For Hypertrophy:

  • Training close to failure appears to offer a hypertrophic benefit.
  • You don’t necessarily have to go all the way to failure.
  • For practical programming, 1–3 RIR can be a useful starting range for many hypertrophy-oriented sets, although the research does not establish one universal optimal RIR.
  • Proper exercise selection and fatigue management still apply.
  • Volume, nutrition, recovery, and progressive overload still matter.

For Strength:

  • Training to failure isn’t required for all sets.
  • Higher intensities (i.e., heavier weights) are especially relevant to maximal strength development.
  • Technique and specificity are also more pertinent to training for strength.
  • More reps left in the tank can help you avoid excessive fatigue.

The relationship between proximity-to-failure and strength gains also seems to be weaker than the relationship between proximity-to-failure and hypertrophy.

For Both:

You don’t have to pick one or the other.

A good program can involve using heavier, less-fatiguing sets for developing strength, while using closer-to-failure moderate sets for hypertrophy.

A Simple Rule to Remember

If you’re pursuing hypertrophy, don’t make all of your sets easy.

If you’re focusing on strength, don’t assume all of your sets must finish in failure.

And if you’re doing both, don’t use the same effort level for different exercises and training goals.

The most important takeaway from the recent failure training study isn’t that failure is good or bad.

It is that the proximity to failure appears to have different effects based on the context and training goals.

Bottom Line

If big muscles are your goal, training reasonably close to failure is a good approach to take. You don’t need to leave every set exhausted and unable to perform another repetition.

If maximum strength is your goal, you have even less reason to train right to failure.

Heavy, high quality repetitions, appropriate technique, adequate recovery, and progressive overload are more important than simply leaving every set as hard as possible.

The Sports Medicine paper helps to put things into perspective, showing that proximity to failure probably has a stronger relationship with hypertrophy than with strength gains.

The researchers also note that their analysis was exploratory, and that the estimates of RIR were imperfect.

More recent research also shows the value in being judicious when considering failure.

The 2026 ACSM position stand, which draws on a very large amount of systematic-review level evidence, found that training to momentary muscle fatigue did not consistently affect training outcomes, while heavier loads for strength and sufficient weekly volume for hypertrophy showed more consistent relationships with adaptation.

So instead of asking:

“Should I always train to failure?”

you should be asking

“How hard should I train this particular exercise to get the stimulus I need without creating unnecessary fatigue?”

This is a much better way to think about resistance training.

And for most lifters, it probably means a mixture of challenging sets, sensible RIR targets, progressive overload, appropriate exercise selection, and adequate recovery to continue to make gains.

Medical and Fitness Disclaimer:

This article provides general educational information and isn’t a substitute for individualized medical advice; see our medical and fitness disclaimer for additional information.

For more information about how we approach health and fitness research and evaluate evidence, see why we trust LeanAndFit.

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